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Optical coherence tomography (OCT) is an invaluable technique to perform noninvasive retinal imaging in small animal models such as mice. It provides virtual cross sections that correlate well with histomorphometric data with the advantage that multiple iterative measurements can be acquired in time line analyses to detect dynamic changes and reduce the amount of animals needed per study.

Original publication

DOI

10.1007/978-1-62703-080-9_5

Type

Journal article

Journal

Methods Mol Biol

Publication Date

2013

Volume

935

Pages

79 - 85

Keywords

Animals, Disease Models, Animal, Equipment Design, Image Processing, Computer-Assisted, Mice, Retina, Retinal Diseases, Software, Tomography, Optical Coherence