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We investigated the therapeutic effects of milacemide in seven patients with myoclonus and three patients with the stiff-person syndrome in an open-label trial. Milacemide was initiated at 800 mg/day and was gradually increased to a maximum dosage of 2,400 mg/day. No significant improvement occurred in the 10 patients.

Original publication

DOI

10.1002/mds.870060114

Type

Journal article

Journal

Mov Disord

Publication Date

1991

Volume

6

Pages

73 - 75

Keywords

Acetamides, Adult, Aged, Anticonvulsants, Female, Humans, Male, Middle Aged, Monoamine Oxidase Inhibitors, Muscle Rigidity, Myoclonus, Neurologic Examination, Spasm, Syndrome