Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Graft versus host disease presents a major obstacle to the widespread application of allogeneic bone marrow transplantation despite improvements in drug prophylaxis. Although animal models are providing an understanding of the biology of the process, opportunities for exploitation of that knowledge for therapeutic purposes are still limited. One way to overcome this impasse is to build on the positive benefits of T-cell purging of marrow, by combining it with intelligent correction of the known negative effects.

Type

Journal article

Journal

Curr Opin Immunol

Publication Date

10/1994

Volume

6

Pages

777 - 783

Keywords

Animals, Bone Marrow Purging, Bone Marrow Transplantation, Graft Rejection, Graft vs Host Disease, Humans, Risk Factors, T-Lymphocyte Subsets