Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

This article provides a summary of the efficacy, and relative efficacy, of 38 different drugs or drug combinations tested in standard postoperative pain trials. It will help clinicians and patients make informed choices about analgesia based on pain relief, duration of action, and adverse events, which can then be put into context for the individual patient, depending on local availability. This article highlights the fact that no single drug is effective in all patients--even the best drugs fail to provide good levels of pain relief in at least 30%. These patients should try a different analgesic.

Original publication




Journal article


Br Dent J

Publication Date





419 - 420


Acetaminophen, Analgesics, Anti-Inflammatory Agents, Non-Steroidal, Drug Combinations, Facial Pain, Humans, Ibuprofen, Molar, Third, Pain, Postoperative, Randomized Controlled Trials as Topic, Review Literature as Topic, Tooth Extraction