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The complete sequence of the rat immunoglobulin gamma 2c heavy chain constant region has been determined by cDNA cloning and by mRNA sequencing. Comparison with other heavy chain genes reveals a high degree of homology (87%) to mouse gamma 3 and suggests that rat and mouse gamma genes separated from a common set of three ancestral genes.

Original publication

DOI

10.1002/eji.1830180222

Type

Journal article

Journal

Eur J Immunol

Publication Date

02/1988

Volume

18

Pages

317 - 319

Keywords

Amino Acid Sequence, Animals, Base Sequence, DNA, Genes, Immunoglobulin, Immunoglobulin Constant Regions, Immunoglobulin G, Immunoglobulin Heavy Chains, Mice, Molecular Sequence Data, Rats, Sequence Homology, Nucleic Acid, Species Specificity