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The HIV-1 epidemic among injecting drug users (IDU) in Taiwan is caused primarily by CRF07_BC infections. Evolutionary analyses, which utilize outgroup reference strains from northwestern China (Xinjiang), reveal that CRF07_BC was introduced into southern Taiwan in 1998-2001 and spread to central-northern Taiwan in 2001-2003, causing the largest HIV/AIDS epidemic in Taiwan. The separate introduction of CRF07_BC into Xinjiang occurred in 1992-1995. This study illustrates the temporal dynamics of CRF07_BC spread among IDU across east Asia.

Original publication

DOI

10.1097/QAD.0b013e3282f2d77a

Type

Journal article

Journal

AIDS

Publication Date

02/01/2008

Volume

22

Pages

156 - 158

Keywords

China, Disease Outbreaks, Genes, Viral, HIV Infections, HIV-1, Phylogeny, Substance Abuse, Intravenous, Taiwan, env Gene Products, Human Immunodeficiency Virus