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The transcription machineries of Archaea and eukaryotes are similar in many aspects, but little is understood about archaeal chromatin and its role in transcription. Here, we describe the identification in hyperthermophilic Crenarchaeota and a Korarchaeon of an orthologue of the eukaryotic transcription elongation factor Elf1, which has been shown to function in chromatin structure maintenance of actively transcribed templates. Our discovery has implications for the relationship of chromatin and transcription in Archaea and the evolution of these processes in eukaryotes.

Type

Journal article

Journal

Biol Direct

Publication Date

29/07/2009

Volume

4

Keywords

Archaea, Archaeal Proteins, Chromatin, Crenarchaeota, Evolution, Molecular, Gene Expression Regulation, Archaeal, Transcription Factors