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We describe the complete nucleotide sequence of the human epsilon-globin gene including 387 nucleotides of 5' flanking sequence and 301 nucleotides of 3' flanking sequence. The arrangement of coding, noncoding and intervening sequences in this gene is entirely consistent with its identification as the embryonic beta-like globin gene.

Type

Journal article

Journal

Cell

Publication Date

10/1980

Volume

21

Pages

621 - 626

Keywords

Amino Acid Sequence, Base Sequence, Cloning, Molecular, DNA, DNA Restriction Enzymes, Genes, Globins, Humans