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This study aimed to examine, using diffusion tensor imaging (DTI), differences in electrode placement in four patients undergoing deep brain stimulation for chronic neuropathic pain of varying aetiology. A pre-operative DTI was obtained for each patient, who was then implanted with deep brain stimulation electrodes in the periventricular/periaqueductal grey area with good pain relief. Using seeds from the postoperative MRI scan, probabilistic tractography was performed from the pre-operative DTI.

Original publication




Journal article


J Clin Neurosci

Publication Date





801 - 805


Brain Mapping, Chronic Disease, Deep Brain Stimulation, Diffusion Magnetic Resonance Imaging, Electrodes, Implanted, Humans, Models, Statistical, Monitoring, Physiologic, Neural Pathways, Pain, Intractable, Periaqueductal Gray, Postoperative Complications, Preoperative Care, Stereotaxic Techniques