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Optical coherence tomography (OCT) is an invaluable technique to perform noninvasive retinal imaging in small animal models such as mice. It provides virtual cross sections that correlate well with histomorphometric data with the advantage that multiple iterative measurements can be acquired in timeline analyses to detect dynamic changes and reduce the number of animals needed per study.

Original publication

DOI

10.1007/978-1-4939-8669-9_18

Type

Chapter

Publication Date

2019

Volume

1834

Pages

285 - 291

Keywords

Animal models, Confocal scanning laser ophthalmoscopy, Morphology, Optical coherence tomography, Retina, Animals, Disease Models, Animal, Image Processing, Computer-Assisted, Mice, Ophthalmoscopy, Phenotype, Retina, Retinal Degeneration, Software, Tomography, Optical Coherence