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The synthesis of mRNA by RNA polymerase II appears coupled to numerous RNA-processing events, based on physical or functional connections revealed by biochemical or genetic tests. New findings were presented at a recent meeting in Spain that begin to illuminate the mechanisms underlying the connections between mRNA processing and specific steps in transcription (initiation, elongation, and termination) as well as recombination.

Original publication

DOI

10.1016/j.cell.2005.01.002

Type

Journal article

Journal

Cell

Publication Date

28/01/2005

Volume

120

Pages

163 - 166

Keywords

Eukaryotic Cells, Nucleic Acid Conformation, RNA Polymerase II, RNA Processing, Post-Transcriptional, RNA Splicing, RNA, Messenger, Spain, Transcription, Genetic, mRNA Cleavage and Polyadenylation Factors