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BACKGROUND: Progressive reading impairment is an early and debilitating symptom of posterior cortical atrophy (PCA) arising from the progressive deterioration of visual processing skills. OBJECTIVE: The goal of this study was to test the effectiveness of a purpose-built reading app (ReadClear) co-produced with people living with PCA and designed to reduce the reading difficulties experienced by this population (e.g., getting lost in the page and missing words when reading). METHODS: Twenty subjects with PCA were included in a cross-over design home-based study aimed at determining whether ReadClear could 1) enhance the subjective reading experience (reading pleasantness) and 2) improve reading accuracy (reducing the number of reading errors) compared with a sham condition (a standard e-reader). RESULTS: Reading using ReadClear provided a better subjective reading experience than sham (p = 0.018, d = 0.5) and significantly reduced the percentage of reading errors (p 

Original publication

DOI

10.3233/JAD-190335

Type

Journal article

Journal

J Alzheimers Dis

Publication Date

2019

Volume

71

Pages

1285 - 1295

Keywords

Assistive technology, dyslexia, posterior cortical atrophy, reading, Atrophy, Cerebral Cortex, Cross-Over Studies, Dyslexia, Female, Humans, Male, Middle Aged, Neurodegenerative Diseases, Neuropsychological Tests, Outcome Assessment, Health Care, Pattern Recognition, Visual, Reading, Self-Help Devices