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The pattern of histone modifications, called the histone code, influences transitions between chromatin states and the regulation of transcriptional activity. Four recent papers describe how plant homeodomain (PHD) finger proteins read part of this code. The PHD finger may promote both gene expression and repression through interactions with trimethylated lysine 4 on histone 3 (H3K4), a universal modification at the beginning of active genes.

Original publication

DOI

10.1016/j.cell.2006.06.028

Type

Journal article

Journal

Cell

Publication Date

14/07/2006

Volume

126

Pages

22 - 24

Keywords

Chromatin, Gene Expression Regulation, Plant, Histones, Homeodomain Proteins, Models, Molecular, Plant Proteins, Protein Structure, Tertiary, Repressor Proteins