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The recently determined structure of a mammalian voltage-gated potassium channel has important implications for our understanding of voltage-sensing and gating mechanisms in channels. It is also the first crystal structure of an overexpressed eukaryotic membrane protein.

Original publication

DOI

10.1016/j.cub.2005.08.054

Type

Journal article

Journal

Curr Biol

Publication Date

20/09/2005

Volume

15

Pages

R771 - R774

Keywords

Kv1.2 Potassium Channel, Models, Molecular, Protein Conformation, Protein Structure, Tertiary