Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The Tat (twin-arginine translocation) protein export system is found in the cytoplasmic membrane of most prokaryotes and is dedicated to the transport of folded proteins. The Tat system is now known to be essential for many bacterial processes including energy metabolism, cell wall biosynthesis, the nitrogen-fixing symbiosis and bacterial pathogenesis. Recent studies demonstrate that substrate-specific accessory proteins prevent improperly assembled substrates from interacting with the Tat transporter. During the transport cycle itself substrate proteins bind to a receptor complex in the membrane which then recruits a protein-translocating channel to carry out the transport reaction.

Original publication

DOI

10.1016/j.mib.2005.02.010

Type

Journal article

Journal

Curr Opin Microbiol

Publication Date

04/2005

Volume

8

Pages

174 - 181

Keywords

Bacteria, Bacterial Proteins, Escherichia coli, Escherichia coli Proteins, Membrane Transport Proteins, Protein Transport