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The Hox gene cluster has a crucial function in body patterning during animal development. How and when this gene cluster originated is being clarified by recent data from Cnidaria, a basal animal phylum. The characterization of Hox-like genes from Hydra, sea anemones and jellyfish has revealed that a Hox gene cluster is extremely ancient, having originated even before the divergence of these basal animals.

Original publication

DOI

10.1038/35047605

Type

Journal article

Journal

Nat Rev Genet

Publication Date

01/2001

Volume

2

Pages

33 - 38

Keywords

Animals, Body Patterning, Cnidaria, Genes, Homeobox, Humans, Hydra, Multigene Family, Phylogeny, Scyphozoa, Sea Anemones