Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Recent work by several groups has significantly expanded our knowledge of the structure, regulation of assembly, and function of components of the extracellular portion of the type III secretion system (T3SS) of Gram-negative bacteria. This perspective presents a structure-informed analysis of functional data and discusses three nonmutually exclusive models of how a key aspect of T3SS biology, the sensing of host cells, may be performed.

Original publication

DOI

10.1073/pnas.0708344105

Type

Journal article

Journal

Proc Natl Acad Sci U S A

Publication Date

06/05/2008

Volume

105

Pages

6507 - 6513

Keywords

Bacterial Proteins, Biosensing Techniques, Models, Biological, Models, Molecular, Protein Structure, Quaternary, Shigella