Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Patients with late paraphrenia or late onset schizophrenia frequently have associated cognitive impairment which may in some cases progress to a recognized dementia. The frequency of the apoE ϵ4 allele is high in individuals who develop Alzheimer's disease. Twenty‐three patients with late paraphrenia were genotyped for ApoE. The frequency of the ϵ4 allele was comparable with that found in a large group of centenarians, but lower than previously reported from populations of normal controls and Alzheimer's disease patients. Two out of three male patients tested had the rare ϵ2/ϵ2 genotype, which was not found in any of the females. Copyright © 1995 John Wiley & Sons, Ltd.

Original publication

DOI

10.1002/gps.930100210

Type

Journal article

Journal

International Journal of Geriatric Psychiatry

Publication Date

01/01/1995

Volume

10

Pages

147 - 150