Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The argos gene encodes a protein that is required for viability and that regulates the determination of cells in the Drosophila eye. A developmental analysis of argos mutant eyes indicates that the mystery cells, which are usually nonneuronal, are transformed into extra photoreceptors, and that supernumerary cone cells and pigment cells are also recruited. Clonal analysis indicates that argos acts nonautonomously and can diffuse over the range of several cell diameters. Conceptual translation of the argos gene suggests that it encodes a secreted protein.

Type

Journal article

Journal

Cell

Publication Date

12/06/1992

Volume

69

Pages

963 - 975

Keywords

Amino Acid Sequence, Animals, Base Sequence, Cell Communication, Clone Cells, Cloning, Molecular, DNA, Drosophila melanogaster, Embryonic Induction, Eye, Gene Expression, Genes, Molecular Sequence Data, Phenotype, RNA, Messenger, Restriction Mapping, Signal Transduction