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Molecular imaging has witnessed an upsurge in growth, with positron emission tomography leading the way. This trend has encouraged numerous synthetic chemists to enter the field of (18) F-radiochemistry and provide generic solutions to address the well-recognized challenges of late-stage fluorination. This Minireview focuses on recent developments in the (18)F-labeling of aromatic substrates.

Original publication

DOI

10.1002/anie.201204687

Type

Journal article

Journal

Angew Chem Int Ed Engl

Publication Date

12/11/2012

Volume

51

Pages

11426 - 11437

Keywords

Fluorine Radioisotopes, Halogenation, Humans, Hydrocarbons, Aromatic, Molecular Imaging, Positron-Emission Tomography