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The human brain forms functional networks of correlated activity, which have been linked with both cognitive and clinical outcomes. However, the genetic variants affecting brain function are largely unknown. Here, we used resting-state functional magnetic resonance images from 47,276 individuals to discover and validate common genetic variants influencing intrinsic brain activity. We identified 45 new genetic regions associated with brain functional signatures (P 

Original publication

DOI

10.1038/s41588-022-01039-6

Type

Journal article

Journal

Nat Genet

Publication Date

04/2022

Volume

54

Pages

508 - 517

Keywords

Alzheimer Disease, Brain, Depressive Disorder, Major, Humans, Magnetic Resonance Imaging, Nerve Net