Guy M. Goodwin FRCPsych, FMedSci
Research Areas
Medical Sciences Division Themes
- Neuroscience
- Behavioural Science
- Imaging
- Drug Discovery
Neuroscience Sub-Themes
- Systems, Cognitive and Behavioural Neuroscience
- Functional Brain Imaging
- Human Psychology, Mental Health and Psychiatry
Neuroscience Keywords
- Affective Neuroscience
- Bipolar Disorder
- Brain Imaging
- Circadian Rhythms
- Clinical Trials
- Cognitive Impairment
- Decision-Making
- Depression
- Depressive Disorders
- Emotion
- Face Perception
- fMRI
- Human
- MEG
- Metabolism
- Neurogenesis
- Prefrontal Cortex
- Psychiatry
- Serotonin
Techniques and Equipment
Collaborators
- Catherine Harmer, PERL, University Dept of Psychiatry
- John Geddes, University Dept of Psychiatry
- Robert Rogers, University Dept of Psychiatry
- Gerry Dawson, P1vital
- David Miklowitz, University of Colorado and University Dept of Psychiatry
| Department |
Department of Psychiatry
Oxford Centre for Functional Magnetic Resonance Imaging of the Brain |
|---|---|
| College | Merton College |
My research interests are in the treatment of bipolar
disorder and the application of neuroscience in understanding the neurobiology
of mood disorder and developing new treatments. I am also developing the capacity
for pragmatic clinical trials in bipolar affective disorder with the BALANCE trial,
which recently finished recruitment and the CEQUEL study starting in 2007. I am active in developing the pre-competitive links with industry required to establish models of psychotropic drug action in man.
Biography
I studied medicine and completed a DPhil in physiology at Oxford. After training in psychiatry I was for 10 years Clinical Scientist and Consultant Psychiatrist in the MRC Brain Metabolism Unit in Edinburgh. I have served as a member of the Wellcome Trust Neurosciences Panel, the Council of the British Association for Psychopharmacology and the Clinical fellowships panel and Advisory Board of the MRC. I am currently a member of INSERM's ANR panel. I was elected president of the British Association for Psychopharmacology for 2004 – 2005 and am a Foreign corresponding fellow of ACNP.
Awards Training and Qualifications
- 1965- 1968 BA (1st Class Hons.), University of Oxford
- 1968- 1972 DPhil, University of Oxford
- 1975- 1978 BM, BCh, University of Oxford
Selected Publications
- Chan S W, Goodwin G M, and Harmer C J (2007) Highly neurotic never-depressed students have negative biases in information processing. Psychol Med:1-11.
- Harmer Catherine J, Mackay Clare E, Reid Catriona B, Cowen Philip J, and Goodwin Guy M (2006) Antidepressant drug treatment modifies the neural processing of nonconscious threat cues. Biol Psychiatry, 59(9):816-20.
- Clark Luke, Kempton Matthew J, Scarna Antonina, Grasby Paul M, and Goodwin Guy M (2005) Sustained attention-deficit confirmed in euthymic bipolar disorder but not in first-degree relatives of bipolar patients or euthymic unipolar depression. Biol Psychiatry, 57(2):183-7.
- Clark Luke, Sarna Antonina, and Goodwin Guy M (2005) Impairment of executive function but not memory in first-degree relatives of patients with bipolar I disorder and in euthymic patients with unipolar depression. Am J Psychiatry, 162(10):1980-2.
- Harvey Allison G, Schmidt D A, Scarna Antonina, Semler Christina N, and Goodwin Guy M (2005) Sleep-related functioning in euthymic patients with bipolar disorder, patients with insomnia, and subjects without sleep problems. Am J Psychiatry, 162(1):50-7.
- Hayward Gail, Goodwin Guy M, Cowen Phil J, and Harmer Catherine J (2005) Low-dose tryptophan depletion in recovered depressed patients induces changes in cognitive processing without depressive symptoms. Biol Psychiatry, 57(5):517-24.
- Gijsman Harm J, Geddes John R, Rendell Jennifer M, Nolen Willem A, and Goodwin Guy M (2004) Antidepressants for bipolar depression: a systematic review of randomized, controlled trials. Am J Psychiatry, 161(9):1537-47.
- Harmer Catherine J, Shelley Nicholas C, Cowen Philip J, and Goodwin Guy M (2004) Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition. Am J Psychiatry, 161(7):1256-63.
- Geddes John R, Carney Stuart M, Davies Christina, Furukawa Toshiaki A, Kupfer David J, Frank Ellen, and Goodwin Guy M (2003) Relapse prevention with antidepressant drug treatment in depressive disorders: a systematic review. Lancet, 361(9358):653-61.
- Scarna A, Gijsman H J, McTavish S FB, Harmer C J, Cowen P J, and Goodwin G M (2003) Effects of a branched-chain amino acid drink in mania. Br J Psychiatry, 182:210-3.
